TheFatal Family Insomnia (FFI) is a very rare disease caused by a mutated protein, the prion, which directly attacks the central nervous system.
This pathology is characterized by insomnia which gets increasingly severe until the total inability to sleep. It is followed by hallucinations, disturbance of the autonomic nervous system, motor disorders and dementia, quickly leading to death.
Until now, no treatment for the fatal familial insomnia was found.